Welcome
We are a group of geneticists, neuroscientists, and computer scientists who are passionate about discoveries of novel targets and models for mental illness through innovation at the confluence of computational, genetic, and genomic methods.
The Kumar Laboratory is located at the Jackson Laboratory in Bar Harbor, Maine. We study neural circuits in the brain whose misregulation leads to behavioral abnormalities including addiction, attention deficit hyperactivity disorder, and depression. Using mouse molecular genetics as a foundation, and a combination of computational, biochemistry, physiology, and imaging techniques, we dissect these complex conditions in mammals.
Primarily, we use functional genomic approaches in mice to identify genes and pathways that regulate these behaviors. We seek to develop better models of human diseases that can be used by the biomedical research community for therapeutics. Recently, we have applied machine learning and artificial intelligence methods to understand animal behavior at high spatial and temporal resolution, objectively, and over long periods of time. Our work has been published in numerous high impact journals such as Science, eLife, Nature Communications Biology, among others.
Latest Lab News and Blogs:
Press Article on Dr. Kumar and Dr. Chesler
https://www.jax.org/news-and-insights/2019/may/jax-scientists-speak-out-on-the-crisis-of-opioid-addiction
Arojit’s paper demonstrating that TMOD2 is a regulator of cocaine responses is on Biorxiv.
The paper is currently under review and we hope it is published soon. Meanwhile, the preprint is available here. https://www.biorxiv.org/content/10.1101/648295v1
Vivek speaks at MDIBL on an opioid crisis panel
MDIBL hosted a meeting of researchers on the opioid crisis in Maine. The panel is part of the 46th Maine Biological and Medical Sciences Symposium (MBMSS), an annual statewide gathering at which students and scientists have the opportunity to network, collaborate,...
Vivek gives a talk at the Discovery Museum in Bridgeport, CT
Vivek gave a talk on the genetics and neuroscience of addiction at the Discovery Museum in Bridgeport, CT. The talk was attended by several dozen museum attendees and organized by JAX government outreach folks. Vivek also met with Connecticut State Representative,...
Brian’s tracking paper published
Brian's paper on robust mouse tracking is published. This paper describes how to track mice in complicated environments. Sean and others contributed to this paper. https://doi.org/10.1038/s42003-019-0362-1 Data from the paper is here. [button...
Vivek speaks at the 2019 Maine State Science Fair
Vivek spoke about addiction genetics and neuroscience to high schools students from across the state of Maine. Over 200 students competed in over a dozen categories in this year's science fair. More information about the event is here. Arojit Mitra was a...
Some useful links